The New York Giants and San Francisco 49ers will compete for a spot in Super Bowl XLVI when they meet Sunday at Candlestick Park. Odds...
New Orleans Saints at San Francisco 49ers OddsThe NFC South champion New Orleans Saints continue their quest for a second Super Bowl title in three years when they take on...
San Francisco 49ers at St. Louis Rams LineThe San Francisco 49ers (12-3) can lock up the No. 2 seed in the NFC playoffs with a win over the St. Louis Rams (2-13) Sunday. Odds...
San Francisco 49ers at Seattle Seahawks SpreadThe Seattle Seahawks (7-7) will be gunning for a fourth straight win when they host the San Francisco 49ers (11-3) Saturday. Odds...
Pittsburgh Steelers at San Francisco 49ers LineThe Pittsburgh Steelers (10-3) will be looking for a fifth straight victory when they visit the San Francisco 49ers (10-3) Monday...
San Francisco 49ers at Arizona Cardinals OddsThe San Francisco 49ers (10-2) will be looking for a 10th victory in 11 games when they visit the surging Arizona Cardinals (5-7)...
St. Louis Rams at San Francisco 49ers SpreadThe San Francisco 49ers (9-2) will be looking to win for the ninth time in 10 games when they host the St. Louis Rams (2-9) Sunday...
San Francisco 49ers at Baltimore Ravens LineThe San Francisco 49ers (9-1) will be gunning for a ninth straight victory when they visit the Baltimore Ravens (7-3) Thanksgiving...
Arizona Cardinals at San Francisco 49ers LineThe San Francisco 49ers (8-1) will be gunning for an eighth straight win when they host the Arizona Cardinals (3-6) Sunday at...
New York Giants at San Francisco 49ers OddsThe San Francisco 49ers (7-1) will be looking for a seventh straight victory when they host the New York Giants (6-2) Sunday at...
San Francisco 49ers at Washington Redskins OddsThe San Francisco 49ers (6-1) will be looking for a sixth straight win when they visit the Washington Redskins (3-4) Sunday. Odds...
Cleveland Browns at San Francisco 49ers SpreadThe San Francisco 49ers (5-1) will be looking for their fifth straight win when they host the Cleveland Browns (3-3) Sunday at...
San Francisco 49ers at Detroit Lions SpreadThe 5-0 Detroit Lions will be trying to remain undefeated when they host the 4-1 San Francisco 49ers Sunday. Odds makers believe...
Tampa Bay Buccaneers at San Francisco 49ers OddsThe Tampa Bay Buccaneers will be looking for their fourth straight win when they visit the 3-1 San Francisco 49ers Sunday. Odds...
San Francisco 49ers at Philadelphia Eagles SpreadThe Philadelphia Eagles, who opened the season among the favorites to win the Super Bowl, find themselves at 1-2 following back-to-back...
San Francisco 49ers at Cincinnati Bengals OddsThe San Francisco 49ers and Cincinnati Bengals are both looking to bounce back from close losses when they meet Sunday at Paul...
Dallas Cowboys at San Francisco 49ers OddsThe Dallas Cowboys are looking to put a Week 1 collapse behind them. The San Francisco 49ers are hoping to improve to 2-0 under...
Seattle Seahawks at San Francisco 49ers LineThe San Francisco 49ers haven’t had a winning season since 2002. They’re hoping new head coach Jim Harbaugh can bring...
2011 San Francisco 49ers PredictionsThe 49ers were the favorites to win the NFC West in 2010, and Mike Singletary was shown the door when they failed to do so. Now,...
2011 San Francisco 49ers ScheduleHere’s the 2011 NFL schedule for the San Francisco 49ers: Week 1 Sun, Sept. 11 vs. Seattle Seahawks FOX 4:15 p.m. –...
2011 San Francisco 49ers NFL Draft NeedsFollowing a disappointing 6-10 season, the San Francisco 49ers are on the clock with the seventh overall pick in the 2011 NFL...
2011 NFL Mock DraftThe 2011 NFL Draft kicks off on Thursday, April 28 and concludes on Saturday, April 30. All the first round selections will be...
Arizona Cardinals at San Francisco 49ers OddsWhat a disappointing campaign it’s been for the San Francisco 49ers, a team most considered to be the favorite to win the...
San Francisco 49ers at St. Louis Rams OddsA quick glance at the records and a casual fan might think this game between 5-9 San Francisco and 6-8 St. Louis doesn’t...
San Francisco 49ers at San Diego Chargers OddsThe San Francisco 49ers and the San Diego Chargers kept their playoff hopes alive with Week 14 wins. Now, the two Golden State...
Seattle Seahawks at San Francisco 49ers NFL PicksThe Seattle Seahawks shocked the San Francisco 49ers with a 31-6 home win in the season opener. That loss sent the preseason favorites...
San Francisco 49ers at Green Bay Packers OddsThe Green Bay Packers and the San Francisco 49ers will both try to keep pace in their respective divisions when they meet at Lambeau...
San Francisco 49ers at Arizona Cardinals NFL OddsDespite entering Monday night’s contest with 3-7 records, the San Francisco 49ers and the Arizona Cardinals still have plenty...
Tampa Bay Buccaneers at San Francisco 49ers OddsThe San Francisco 49ers have put their worst start in over three decades behind them. With three wins in their last four games,...
St. Louis Rams at San Francisco 49ers NFL PicksThe St. Louis Rams went 1-15 last season, but they have already won four games in 2010 and find themselves tied for first place...
Denver Broncos at San Francisco 49ers OddsSo far the season hasn’t gone the way the 2-5 Denver Broncos or the 1-6 San Francisco 49ers would have liked. Both teams...
San Francisco 49ers at Carolina Panthers OddsThe 1-5 San Francisco 49ers finally broke into the win column last week with a 17-9 victory over Bay Area rival Oakland. Now,...
Oakland Raiders at San Francisco 49ers OddsThe Oakland Raiders and the San Francisco 49ers are all set to do battle for Bay Area bragging rights when they meet in a Week...
Philadelphia Eagles at San Francisco 49ers OddsPhiladelphia Eagles quarterback Michael Vick made the most of his opportunity when starting quarterback Kevin Kolb left with a...
San Francisco 49ers at Atlanta Falcons SpreadA San Francisco 49ers team that was the preseason favorite to win the NFC West has been one of the biggest disappointments thus...
San Francisco 49ers Kansas City Chiefs OddsThe San Francisco 49ers will be looking for their first win when they visit the unbeaten Kansas City Chiefs at Arrowhead Sunday....
New Orleans Saints at San Francisco 49ers OddsThe defending Super Bowl champion New Orleans Saints began their title defense with a hard-fought win over the Minnesota Vikings...
San Francisco 49ers at Seattle Seahawks NFL PicksThe San Francisco 49ers and the Seattle Seahawks are all set to kick off their 2010 campaigns Sunday in an NFC West division battle....
2010 San Francisco 49ers PredictionsNow that former Arizona Cardinals quarterback Kurt Warner has called it quits, NFL odds makers believe the NFC West will crown...
2010 NFL PredictionsBelow, I have made my NFL picks on which teams I like to win their respective divisions in 2010. Be sure to take these predictions...
2010 NFL Mock Draft: San Francisco 49ersWith two first round draft picks, the San Francisco 49ers have the opportunity to really help their chances this season. The 49ers...
San Francisco 49ers at Philadelphia Eagles NFL Predictions & OddsThe 6-7 San Francisco 49ers look to build on Monday night’s big win over the Cardinals when they visit the 9-4 NFC East...
Arizona Cardinals at San Francisco 49ers NFL Betting & OddsThe 8-4 Arizona Cardinals take on the 5-7 San Francisco 49ers in a Week 14 NFC West Division showdown on ESPN’s Monday Night...
San Francisco 49ers at Green Bay Packers NFL Week 11 Odds & BettingThe 4-5 San Francisco 49ers take on the 5-4 Green Bay Packers this Sunday at legendary Lambeau Field in a Week 11 NFC battle....
Chicago Bears at San Francisco 49ers OddsThe 4-4 Chicago Bears take on the 3-5 San Francisco 49ers at Monster Park in the second Thursday night game of the season in a...
Tennessee Titans at San Francisco 49ers LineThe 1-6 Tennessee Titans head west to take on the 3-4 San Francisco 49ers this Sunday in a Week 9 AFC versus NFC clash. Last week,...
San Francisco 49ers at Indianapolis Colts OddsThe San Francisco 49ers look to get back on track after back-to-back losses, but it will be no easy task against the undefeated...
San Francisco 49ers at Houston Texans OddsThe San Francisco 49ers head to Houston to take on the Texans in a Week 7 non-conference clash this Sunday. Last week, Houston...
Atlanta Falcons at San Francisco 49ers NFL Spread & PicksThe 2-1 Atlanta Falcons make the cross-country trip to take on the 3-1 San Francisco 49ers this Sunday in a Week 5 NFC non-division...
St. Louis Rams at San Francisco 49ers NFL Lines & PredictionsThe 0-3 St. Louis Rams take on the 2-1 San Francisco 49ers this Sunday at Monster Park in a Week 4 NFC West showdown. Last week,...
